Bastien Boussau



 

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Research Overview

I am interested in developing and using integrative approaches to tackle evolutionary questions in a statistical framework, through bioinformatics. Here, "integrative approach" means e.g. jointly inferring alignment and phylogeny, gene trees and organism tree, or organism tree and ancestral characters. I am currently working on these last two problems.

Selected Publications

Boussau B., Daubin V. In press. "Genomes as documents of evolutionary history." Trends Ecol. Evol.

Boussau B. 2009. "Phylogenetic relationships deduced from whole genome comparisons." Encyclopaedia of Life Sciences, John Wiley & Sons, Ltd: Chichester [Doi: 10.1002/9780470015902.a0021784].

Boussau B., Guéguen L., Gouy M. 2008. "A Mixture Model and a Hidden Markov Model to Simultaneously Detect Recombination Breakpoints and Reconstruct Phylogenies." Evolutionary Bioinformatics, 5 67-79.

Douard V., Brunet F., Boussau B., Ahrens I., Vlaeminck-Guillem V., Haendler B., Laudet V., Guiguen Y. 2008. "The fate of the duplicated androgen receptor in fishes: a late neofunctionalization event?" BMC Evol. Biol., 8:336.

Boussau B., Blanquart S., Necsulea A., Lartillot N., Gouy M. 2008. "Parallel adaptations to high temperatures in the archean eon." Nature, 456(7224):9425.

Boussau B., Guéguen L., Gouy M. 2009. "Accounting for horizontal gene transfers explains conflicting hypotheses regarding the position of Aquificales in Bacterial phylogeny." BMC Evol. Biol., 8:272.

Dutheil J., Boussau B. 2008. "Nonhomogeneous models of sequence evolution in the Bio++ suite of libraries and programs" BMC Evol. Biol., ;8:255.

Brochier-Armanet C., Boussau B., Gribaldo S., Forterre P. 2008. "Mesophilic crenarchaeota: proposal for a third archaeal phylum, the Thaumarchaeota." Nat. Rev. Microbiol. 6:24552.

Boussau B., Gouy M. 2006. "Efficient likelihood computations with nonreversible models of evolution." Syst. Biol. 55:75668.

Boussau B., Karlberg E.O., Frank A.C., Legault B., Andersson S.G. 2004. "Reconstruction of the alpha-Proteobacterial ancestor." Proc. Natl. Acad. Sci. USA 101:97229727.

Robinson-Rechavi M., Boussau B., Laudet V. 2004. "Phylogenetic dating and characterization of gene duplications in vertebrates: the cartilaginous fish reference." Mol. Biol. Evol. 21: 5806.