Raquel Assis



Research Overview

My research focuses on the origin of genetic and phenotypic novelty. During my graduate career, I employed a comparative phylogenetic approach to investigate the evolution of novel genes. As a postdoctoral fellow, I have been studying the emergence of new phenotypes by using gene expression as a proxy for function. While my main interests lie in gene duplication, which is a key mechanism by which genetic innovation arises, I am also interested in the evolution of functional novelty via modification of the regulation and expression of existing genes.

Selected Publications

Assis R, Zhou Q, Bachtrog D. Sex-biased transcriptome evolution in Drosophila. Genome Biology and Evolution. Accepted (2012).

Assis R, Kondrashov AS. Nonallelic gene conversion is not GC-biased in Drosophila or primates. Molecular Biology and Evolution 29: 291-1295 (2012).

Assis R, Kondrashov AS. A strong deletion bias in nonallelic gene conversion. PLoS Genetics 8: e1002508 (2012).

Kondrashov AS, Assis R. Bridges: A tool for identifying local similarities in long sequences. Bioinformatics 26: 2055-2056 (2010).

Assis R, Kondrashov AS. Rapid repetitive element-mediated expansion of piRNA clusters in mammalian evolution. Proceedings of the National Academy of Sciences of the United States of America 106: 7079-7082 (2009).

Assis R, Kondrashov AS, Koonin EV, Kondrashov FA. Nested genes and increasing organizational complexity of metazoan genomes. Trends in Genetics 23: 475-478 (2008).